Cell 0135% backed
Passionflower
Passiflora incarnata
Label: 145 mg per 2 capsulesThe best-studied herb on the label. In small randomized trials, 36 adults with generalized anxiety did about as well on passionflower drops as on oxazepam over four weeks [2], 60 surgical patients given 500 mg before an operation reported less anxiety than those on placebo [4], and a polysomnography trial in 110 adults with insomnia recorded longer total sleep time [11]. A 2020 systematic review called the results promising and the trials small [12].
For nerve pain the human record is empty. The neuropathic data come from rats, where an extract eased allodynia through GABA and opioid pathways [13].
Shown: modest calming and sleep effects in short trials. Hypothesis: any direct effect on nerve pain, numbness or tingling.


